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Director, HEOR

Director, HEOR

  • Remote
  • Full-Time
  • Director
Location: Remote

Who We Are

Enzyvant is a commercial-stage biotechnology company on the leading edge of regenerative medicine for rare diseases. Our lead asset is FDA-approved RETHYMIC®, a tissue-based regenerative therapy for an ultra-rare and life-threatening pediatric immunodeficiency. It is an exciting time for the Enzyvant team as we deliver on our patient purpose and execute on our bold vision for growth.

Patients are the heart and soul of Enzyvant, inspiring deep meaning, passion, and purpose in our work. They are all the reasons for why, how, and what we do. At Enzyvant, we see a world where the promise of our breakthrough biotechnologies is fully realized to transform the lives of patients battling devastating rare diseases. To achieve this vision, we are pursuing new uses and geographies for our biotechnologies and providing extensive support to help families navigate the complexity of rare diseases with our Enzyvant Connect program.

The Enzyvant team includes some of the most innovative talent in the regenerative medicine sector today. We attract people in biotech who want to make their mark in regenerative medicine and deliver truly meaningful, life-changing solutions for patients. Our company culture values teamwork, innovation, empowerment, and integrity. Enzyvant has a small company feel with the reach and resources of our global parent company Sumitovant Biopharma Ltd. (wholly owned by Sumitomo Dainippon Pharma Co., Ltd.)


The Director, HEOR leads the strategic development and execution of health economics and outcomes research and evidenced-based strategies to support current and future Enzyvant products.  This role reports to the Vice President, Market Access.


  • Lead the development and execution of the evidence generation strategy to support the clinical and economic value of Enzyvant products, in collaboration with cross functional partners
  • Through key leadership and partnership across cross-functional teams, the Director, HEOR embeds HEOR strategy into broader disease area and clinical development strategies
  • Build strategies to demonstrate and differentiate the value proposition and corresponding scientific evidence of Enzyvant products, for payers, patients, clinical institutions, and other key influencers
  • Utilize in-depth knowledge of disease area and portfolio strategy in combination with health economics and outcomes research to develop and execute the HEOR strategy
  • Ensures payer relevant endpoints and evidence generation strategies are implemented throughout the product lifecycle
  • Build collaborative relationships with cross-functional leaders across Research & Development, Commercial, Market Access organizations to maximize evidence generation efforts to optimize launch and sustained reimbursement throughout the product lifecycle
  • Lead the development of key deliverables (dossiers, economic models and value propositions) that differentiate assigned products for payers, policymakers, healthcare providers, and market access stakeholders
  • Ensure Enzyvant maintains external credibility and relationships to validate research findings and communications
  • Execute on US and global HEOR strategies and programs, advise and support clinical development and research, regulatory, marketing, and market access activities
  • Cultivate and maintain relationships with key experts, influencers, and customer segments to foster and maintain Enzyvant’s credibility to support the value of Enzyvant products
  • Coordinate and deliver scientific, pharmacoeconomic and disease awareness information on behalf of Enzyvant at various industry and scientific forums to include scientific exchanges with national and regional managed care organizations, pharmacy benefits management companies, government payers and others involved in healthcare policy, disease management/improvement, comparative effectiveness, and medication formulary decisions
  • Develop best practices in HEOR including approaches to areas including research methodologies, study designs, endpoints that provide scientifically sound protocols, policies, tools, and outcome impact
  • Identify areas for process improvements, economies of scale, and other quality and efficiency measures


  • Graduate degree (PhD, MS, BSc/MBA or PharmD) in medicine, pharmacy, life sciences, economics, or public health
  • 8+ years prior experience in HEOR or Market Access in the life sciences industry
  • Deep understanding of the global market access landscape and the US health care environment
  • Experience developing payer-relevant evidence, including real world evidence
  • Strong expertise required in design and conduct of HEOR studies and models
  • Experience conducting health economics, epidemiological, comparative effectiveness, population management, or related research in various disease or policy areas
  • Rare disease experience preferred
  • Experience with one-time therapies a plus


  • Knowledge of the drug development and commercialization process
  • Strong knowledge of major markets and their Health Technology Assessment (HTA) policies
  • Strong presentation and communication skills
  • Build strong, open, and collaborative working relationships with both internal and external stakeholders
  • Proficient in Microsoft Excel, PowerPoint and Word

Contact us for more information